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N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide

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N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:EN450
CAS:793719-01-4
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:EN450
CAS:793719-01-4
Purity:99.72% Package:1mg;39USD|5mg;89USD|10mg;147USD
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:EN450
CAS:793719-01-4
Purity:98% Package:$37.9/1mg;$151.9/10mg;$423.9/50mg;$635.9/100mg;$1334.9/5mg;$2001.9/25mg;Bulk pac Remarks:98%
Company Name: Shanghai Rechem science Co., Ltd.  
Tel: 21-31433387 15618786686
Email: sales@rechemscience.com
Products Intro: CAS:793719-01-4
Purity:98% Package:1g;5g
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: 021-QQ：65489617 15618227136
Email: Sales@ATKchemical.com
Products Intro: Product Name:EN450
CAS:793719-01-4
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G

N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide manufacturers

  • EN450
  • EN450 pictures
  • $39.00 / 1mg
  • 2024-11-19
  • CAS:793719-01-4
  • Min. Order:
  • Purity: 99.72%
  • Supply Ability: 10g
N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide Basic information
Product Name:N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide
Synonyms:N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide;EN450;N-(2-Chloro-5-(N,N-dimethylsulfamoyl)phenyl)acrylamide
CAS:793719-01-4
MF:C11H13ClN2O3S
MW:288.75
EINECS:
Product Categories:
Mol File:793719-01-4.mol
N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide Structure
N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide Chemical Properties
density 1.364±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
storage temp. 2-8°C
solubility DMSO: 2mg/mL, clear
form Solid
pka12.16±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide Usage And Synthesis
Biological ActivityEN450 is a molecular glue degraders of the oncogenic transcription factor NFKB1 th at induces ternary complex formation between ubiquitin-conjugating enzyme E2D1 (UBE2D1) and NFKB1. EN450 covalently modifies an allosteric C111 in UBE2D1 and significantly reduces NFKB1 p105 levels. It impairs leukemia cell viability in a NEDDylation and proteasome-dependent manner at 50 μM.
N-[2-Chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide Preparation Products And Raw materials
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