| Company Name: |
Zhejiang Huida Biotech Co., LTD
|
| Tel: |
0571-89903882 13626641628 |
| Email: |
jiangnan@huidabiotech.com |
| Products Intro: |
Product Name:Ilicicolin H
CAS:12689-26-8
Purity:99% HPLC Package:10mg；100mg；1g；10g；100g
|
| Company Name: |
Zhejiang Huida Biotech Co., LTD
|
| Tel: |
0571-0571-89903882 15990081639 |
| Email: |
sunshixuan@huidabiotech.com |
| Products Intro: |
Product Name:Ilicicolin H
CAS:12689-26-8
Purity:99% HPLC Package:10mg；100mg；1g；10g；100g
|
| Company Name: |
Focus Biomolecules
|
| Tel: |
855-362-8721 |
| Email: |
sales@focusbiomolecules.com |
| Products Intro: |
Product Name:Ilicicolin H
CAS:12689-26-8
Purity:95% by HPLCNMR (Conforms) Package:$120.00/100ug;$750.00/1mg;
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| | ilicicolin H Basic information |
| Product Name: | ilicicolin H | | Synonyms: | ilicicolin H;4-Hydroxy-5-(4-hydroxyphenyl)-3-[[(1R)-1,2,4aα,5,6,7,8,8aβ-octahydro-4,7α-dimethyl-1-[(E)-1-propenyl]naphthalen-2α-yl]carbonyl]pyridin-2(1H)-one;2(1H)-Pyridinone, 4-hydroxy-5-(4-hydroxyphenyl)-3-[[(1R,2S,4aS,7S,8aR)-1,2,4a,5,6,7,8,8a-octahydro-4,7-dimethyl-1-(1E)-1-propen-1-yl-2-naphthalenyl]carbonyl]- | | CAS: | 12689-26-8 | | MF: | C27H31NO4 | | MW: | 433.54 | | EINECS: | | | Product Categories: | | | Mol File: | 12689-26-8.mol |  |
| | ilicicolin H Chemical Properties |
| Boiling point | 630.1±55.0 °C(Predicted) | | density | 1.231±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO | | form | amorphous solid | | pka | 4.50±1.00(Predicted) | | color | Yellow | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| | ilicicolin H Usage And Synthesis |
| Description | Ilicicolin H (12689-26-8) is a potent inhibitor of the mitochondrial cytochrome bc1 reductase.1 Displays potent and broad spectrum antifungal activity.2 | | Definition | ChEBI: Ilicicolin H is an aromatic ketone in which the ketone carbonyl group is attached to a (1R,2R,4aS,7S,8aR)-4,7-dimethyl-1-[(1E)-prop-1-en-1-yl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-2-yl group and a 4-hydroxy-5-(4-hydroxyphenyl)-2-oxo-1,2-dihydropyridin-3-yl group. Isolated from the from the "imperfect" fungus Cylindrocladium iliciola strain MFC-870. It has a role as an antimicrobial agent and a mitochondrial respiratory-chain inhibitor. It is a member of phenols, a pyridone, an aromatic ketone, a monohydroxypyridine, a carbobicyclic compound, a member of octahydronaphthalenes and an ilicicolin. | | References | 1) Singh et al. (2013), Structure-activity relationship of cytochrome bc1 reductase inhibitor broad spectrum antifungal ilicicolin H; Bioorg. Med. Chem., 23 3018
2) Singh et al. (2012), Antifungal spectrum, in vivo efficacy, and structure-activity relationship of ilicicolin h; ACS Med. Chem. Lett., 3 814 |
| | ilicicolin H Preparation Products And Raw materials |
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