siomycin A

siomycin A Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Siomycin A
CAS:12656-09-6
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: AFINE CHEMICALS LIMITED
Tel: +86-0571-85134551
Email: sales@afinechem.com
Products Intro: Product Name:SIOMYCIN A
CAS:12656-09-6
Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Siomycin A
CAS:12656-09-6
Purity:>95% by HPLC Remarks:BOC Sciences also provides custom synthesis services for Siomycin A.
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:Siomycin A
CAS:12656-09-6
Purity:NLT 98% Remarks:MC515530
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:Siomycin A
CAS:12656-09-6
Package:500μg;990USD

siomycin A manufacturers

  • Siomycin A
  • Siomycin A pictures
  • $990.00 / 500μg
  • 2024-10-24
  • CAS:12656-09-6
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
siomycin A Basic information
Product Name:siomycin A
Synonyms:Antibiotic 6741-21;Mutabillicin;Mutabilycin;siomycin A;Mutabilycin, SporangioMycin, 6741-21, Mutabillicin;AKFVOKPQHFBYCA-OFENGFFDSA-N;Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-valyl-2,3-didehydroalanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexa...;Salomycin A
CAS:12656-09-6
MF:C71H81N19O18S5
MW:1648.84
EINECS:
Product Categories:
Mol File:12656-09-6.mol
siomycin A Structure
siomycin A Chemical Properties
density 1.65±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: complete10 mg/ml, clear, colorless to faintly yellow
form White solid.
pka10.43±0.46(Predicted)
Safety Information
WGK Germany 3
MSDS Information
siomycin A Usage And Synthesis
UsesSiomycin A is an antibiotic that inhibits FoxM1.
UsesSiomycin is a macrocyclic antibiotic with potent and selective antibacterial activity discovered in 1969. Siomycin is a potent inhibitor of the oncogenic transcription factor, FoxM1. The reduced transcription activity is reflected in the down regulation of protein and mRNA levels of FoxM1 and effects on down stream genes, Cdc25B, survivin and CENPB. In vitro, siomycin inhibits FoxM1-induced cell growth on soft agar and selectively kill transformed but not normal cells.
siomycin A Preparation Products And Raw materials
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