Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
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Products Intro: |
Purity:IgG fraction of antiserum, lyophilized powder Remarks:affinity isolated antibody, buffered aqueous solution
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Company Name: |
SIGMA-RBI
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Tel: |
800 736 3690 (Orders) |
Email: |
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Products Intro: |
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| ANTI-P300/CBP ASSOCIATED FACTOR, RABBIT Basic information |
Product Name: | ANTI-P300/CBP ASSOCIATED FACTOR, RABBIT | Synonyms: | ANTI-P300/CBP ASSOCIATED FACTOR, RABBIT;ANTI-PCAF RABBIT;Anti-p300/CBP associated factor;Anti-PCAF antibody produced in rabbit | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| ANTI-P300/CBP ASSOCIATED FACTOR, RABBIT Chemical Properties |
storage temp. | -20°C | form | buffered aqueous solution |
Hazard Codes | Xn | Risk Statements | 21/22 | Safety Statements | 36/37 | WGK Germany | - |
| ANTI-P300/CBP ASSOCIATED FACTOR, RABBIT Usage And Synthesis |
Uses | Anti-PCAF antibody is also suitable for use microarray, immunoblot, chemiluminescent western blot (1:500 using whole extracts of dog MDCK kidney cells), and immunoprecipitation (5-10 μg using RIPA lysate with approx. 4x10,000,000 human acute T cell leukemia Jurkat cells). | General Description | PCAF (p300/CBP associated factor, P/CAF), a type A histone acetyltransferases (HAT), has been identified in several species. Human PCAF is a ubiquitous protein member of the GCN5-related N-acetyltransferase (GNAT) superfamily. | Biochem/physiol Actions | PACF (p300/CBP association factor) functions as a transcriptional coactivator in association with p300 and CBP (CREB-binding protein). PCAF share high degree of sequence similarity with human and mouse GCN5 HAT (Histone acetyltransferases). PACF mediates the acetylation of core histone. It is also known for the acetylation of non-histone proteins such as p53, MyoD, TFIIE-b, TFIIE, GATA-1, EKLF, HMGI (Y), and several other cellular and viral proteins. PCAF possesses chromatin modification activity and modulation of transcription factors for the activation of transcription. It also promotes cell growth and development as myogenesis and also contribute to receptor-mediated cell signaling or activation. |
| ANTI-P300/CBP ASSOCIATED FACTOR, RABBIT Preparation Products And Raw materials |
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