Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:ANTI-P53 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Monoclonal Anti-p53 Purity:monoclonal PAb1801, purified from hybridoma cell culture Package:25μL, 200μL Remarks:P6749
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| ANTI-P53 Basic information |
| ANTI-P53 Chemical Properties |
storage temp. | −20°C | form | buffered aqueous solution |
Hazard Codes | Xn | Risk Statements | 21/22 | Safety Statements | 36/37 | WGK Germany | 3 |
| ANTI-P53 Usage And Synthesis |
Uses | Monoclonal Anti-p53-Biotin antibody produced in mouse has been used for Western Blotting. | Uses | Anti-TP53 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. | General Description | p53 is a tumor suppressor gene expressed in a wide variety of tissues. It is a tetrameric nuclear DNA-binding phosphoprotein. The gene encoding it is localized on human chromosome 17p13.1 and mouse chromosome 11.
| Biochem/physiol Actions | Tumor suppressor p53 has the capability to induce cell cycle arrest and has a role in DNA repair, senescence and apoptosis. It binds to Simian vacuolating virus 40 (SV40) T-antigen and human papilloma virus E6 protein. The p53 gene is mutated in various cancers, such as of the breast, ovarian, bladder, colon and lung. |
| ANTI-P53 Preparation Products And Raw materials |
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