| Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
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| Tel: |
0717-6449896 13886658719 |
| Email: |
root@zhongyitai.com |
| Products Intro: |
Product Name:Ceramide Galactoside
CAS:536-13-0
Purity:98+% Package:10mg
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| | kerasin Basic information |
| Product Name: | kerasin | | Synonyms: | Cerasine;N-[(1R,2S,E)-1-[(β-D-Galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]tetracosanamide;Galactosylcerebrosides (non-hydroxy);Galactosylceramides (non-hydroxy);Galactosylceramide (non-hydroxy) (bovine) | | CAS: | 536-13-0 | | MF: | C48H91NO8 | | MW: | 810.23804 | | EINECS: | | | Product Categories: | | | Mol File: | 536-13-0.mol |  |
| | kerasin Chemical Properties |
| storage temp. | Store at -20°C | | solubility | CHCl3:CH3OH:H2O (3:2:1): Soluble | | form | A solid |
| | kerasin Usage And Synthesis |
| Description | Galactosylceramides are glycosphingolipids that contain galactose attached to a ceramide containing an N-acyl hydroxy or non-hydroxy fatty acid. They are metabolic precursors to sulfatide , found primarily in nerve tissues, and are the main glycosphingolipids in the central nervous system.1,2 Galactosylceramides are involved in a multitude of cellular processes including cell agglutination, cellular signaling in glycosynapses, cellular development, and activation of T cells.1,2,3 They accumulate in globoid cells in the brain of patients with Krabbe disease, a disorder characterized by a deficiency in galactosylcerebrosidase activity.2 This product contains non-hydroxy galactosylceramides with primarily C24:0 and C24:1 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. | | Definition | ChEBI: Beta-D-galactosyl-N-(tetracosanoyl)sphingosine is a N-acyl-beta-D-galactosylsphingosine in which the acyl group is tetracosananoyl. It has a role as a mouse metabolite. It is functionally related to a tetracosanoic acid. | | References | 1. Boggs, J.M., Gao, W., Zhao, J., et al. Participation of galactosylceramide and sulfatide in glycosynapses between oligodendrocyte or myelin membranes FEBS Lett. 584(9),1771-1778(2010).
2. Wenger, D.A., Rafi, M.A., and Luzi, P. Krabbe disease: One hundred years from the bedside to the bench to the bedside J. Neurosci. Res. 94(11),982-989(2016).
3. Birkholz, A.M., Howell, A.R., and Kronenberg, M. The α and Ω of galactosylceramides in T cell immune function J. Biol. Chem. 290(25),15365-15370(2015). |
| | kerasin Preparation Products And Raw materials |
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