Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
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Products Intro: |
Remarks:clone 1D11, purified immunoglobulin, buffered aqueous solution
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Company Name: |
SIGMA-RBI
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Tel: |
800 736 3690 (Orders) |
Email: |
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Products Intro: |
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| Anti-EXP, Anti-KIAA0428, Anti-Muscleblind-like protein, Anti-Triplet-expansion RNA-binding protein, Anti-CUG Triplet Repeat Expansion Double-stranded RNA-binding protein Basic information |
| Anti-EXP, Anti-KIAA0428, Anti-Muscleblind-like protein, Anti-Triplet-expansion RNA-binding protein, Anti-CUG Triplet Repeat Expansion Double-stranded RNA-binding protein Chemical Properties |
| Anti-EXP, Anti-KIAA0428, Anti-Muscleblind-like protein, Anti-Triplet-expansion RNA-binding protein, Anti-CUG Triplet Repeat Expansion Double-stranded RNA-binding protein Usage And Synthesis |
Uses | Monoclonal Anti-MBNL1 antibody produced in mouse has been used in: immunoblotting, immunohistochemistry and immunocytochemistry | General Description | Muscle blind-like 1 (MBNL1) is a homolog of human muscle blind like proteins. Proteins of the MBNL (muscleblind-like) family are mainly expressed in skeletal muscle neuronal tissues, thymus, liver and kidney. | Biochem/physiol Actions | Proteins of the MBNL (muscleblind-like) family enhance inclusion or exclusion of specific exons on different pre-mRNAs by inhibiting the activity of CUG-BP and ETR-3-like factors (CELF proteins) bound to distinct intronic sites. MBNL1 may be implicated in the stimulation of muscle differentiation. Mice knockouts for the MBNL1 gene develop muscle, eye, and RNA splicing abnormalities that are characteristic of the neuromuscular disease myotonic dystrophy (DM) disease. |
| Anti-EXP, Anti-KIAA0428, Anti-Muscleblind-like protein, Anti-Triplet-expansion RNA-binding protein, Anti-CUG Triplet Repeat Expansion Double-stranded RNA-binding protein Preparation Products And Raw materials |
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