Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
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Products Intro: |
Remarks:Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1
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Company Name: |
SIGMA-RBI
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Tel: |
800 736 3690 (Orders) |
Email: |
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Products Intro: |
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| Anti-ER degradation enhancer, mannosidase alpha-like 3 Basic information |
Product Name: | Anti-ER degradation enhancer, mannosidase alpha-like 3 | Synonyms: | Anti-EDEM3 (C-terminal) antibody produced in rabbit;Anti-ER degradation enhancer, mannosidase alpha-like 3;Anti-EDEM3 antibody produced in rabbit;Anti-ER degradation-enhancing alpha-mannosidase-like 3 | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| Anti-ER degradation enhancer, mannosidase alpha-like 3 Chemical Properties |
| Anti-ER degradation enhancer, mannosidase alpha-like 3 Usage And Synthesis |
Uses | Anti-EDEM3 (C-terminal) antibody produced in rabbit is suitable for immunoprecipitation at a concentration of 1-2μL using mouse 3T3 cell lysates and western blotting (at a dilution of 1:1,000-1:2,000 using whole extract of human HEK-293T cells and at a dilution of 1:500-1:1,000 using whole extrct of rat PC12 cells). | Biochem/physiol Actions | ER degradation-enhancing α-mannosidase-like 3 is an enzyme encoded by the EDEM3 gene in humans and consists of 931 amino acids. It consists of motifs of Class I α-mannosidases (glycosyl hydrolase family 47) in its N-terminal domain and a protease-associated motif in its C-terminal region. EDEM3 has α1,2-mannosidase activity. EDEM3 is also aasociated with folding-incompetent proteins carrying N-glycans that are extracted from futile folding cycles in the calnexin chaperone system. |
| Anti-ER degradation enhancer, mannosidase alpha-like 3 Preparation Products And Raw materials |
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