Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
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Products Intro: |
Remarks:IgG fraction of antiserum, buffered aqueous solution
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Company Name: |
SIGMA-RBI
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Tel: |
800 736 3690 (Orders) |
Email: |
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Products Intro: |
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| ANTI-MCH RABBIT Basic information |
Product Name: | ANTI-MCH RABBIT | Synonyms: | ANTI-MELANIN-CONCENTRATING HORMONE, RABBIT;ANTI-MCH RABBIT;Anti-MCH antibody produced in rabbit | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| ANTI-MCH RABBIT Chemical Properties |
storage temp. | -20°C | form | buffered aqueous solution |
| ANTI-MCH RABBIT Usage And Synthesis |
Uses | Anti-MCH antibody produced in rabbit has been used in radioimmunoassay and immunohistochemistry. | General Description | Melanin-concentrating hormone (MCH) is a circulating 19-amino acid residue cyclic neuropeptide present in hypothalamus. In mammals, MCH is a, encoded by the precursor pro-melanin concentrating hormone (PMCH). It was first discovered in fish and subsequently in mammalian (rat). MCH perikarya is confined largely to the lateral hypothalamus area (LHA) and the adjacent zon incerta with extensive neuronal projections throughout the brain. MCH is detected in basal ganglia, neocortex, cerebellum, thymus, brown adipose tissue, duodenum, and testis. The structure of MCH is highly conserved among species. | Biochem/physiol Actions | MCH mRNA is overexpressed and up-regulated during fasting in the hypothalamus of ob/ob mice as well as rats. Injection of MCH into the lateral ventricles in rats promote increased food consumption. In addition, knockout mice lacking MCH gene are lean and hypophagic and show an increase in metabolic rate. In contrast, overexpression of MCH in transgenic mice leads to obesity and insulin resistance. |
| ANTI-MCH RABBIT Preparation Products And Raw materials |
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