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| | S(-)-PINDOLOL Basic information |
| Product Name: | S(-)-PINDOLOL | | Synonyms: | L-PINDOLOL;(S)-1-(1H-INDOL-4-YLOXY)-3-[(1-METHYLETHYL)AMINO]-2-PROPANOL;S(-)-PINDOLOL;(-)-PINDOLOL B-ADRENERGIC BLOCKING;2-Propanol, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-, (2S)- (9CI);2-Propanol, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-, (S)-;(2S)-1-(1H-Indole-4-yloxy)-3-(isopropylamino)propane-2-ol;(S)-1-(1H-Indole-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol | | CAS: | 26328-11-0 | | MF: | C14H20N2O2 | | MW: | 248.32 | | EINECS: | | | Product Categories: | Adrenergics;Antagonists;Neurotransmitters | | Mol File: | 26328-11-0.mol |  |
| | S(-)-PINDOLOL Chemical Properties |
| Boiling point | 457.1±35.0 °C(Predicted) | | density | 1.152±0.06 g/cm3(Predicted) | | storage temp. | Desiccate at +4°C | | solubility | 0.1 M NaOH: 0.2 mg/mL | | form | solid | | pka | 13.94±0.20(Predicted) | | color | white | | optical activity | [α]23/D 4.38°, c = 1% in methanol(lit.) |
| | S(-)-PINDOLOL Usage And Synthesis |
| Uses | (S)-(-)-Pindolol is a SR-1A/SR-1B antagonist. | | Definition | ChEBI: (S)-(-)-pindolol is a pindolol. It is an enantiomer of a (R)-(+)-pindolol. | | Biological Activity | 5-HT 1A/1B ? receptor antagonist, with roughly equal affinity for each subtype. A partial agonist at mouse and human β 3 -adrenoceptors. More active enantiomer of pindolol (1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol ). | | storage | Desiccate at +4°C |
| | S(-)-PINDOLOL Preparation Products And Raw materials |
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