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| TETRABENAZINE Basic information |
Product Name: | TETRABENAZINE | Synonyms: | 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-diMethoxy-3-(2-Methylpropyl)-;3-Isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one;Tetrabenazine (Racemate);Tetrabenazine Racemate, >98%;Ro 1-9569 Racemate;TETRABENAZINE RACEMATE;RO 1-9569 RACEMATE;Tetrabenazine Impurity 10;3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2, | CAS: | 718635-93-9 | MF: | C19H27NO3 | MW: | 317.42 | EINECS: | | Product Categories: | | Mol File: | 718635-93-9.mol | ![TETRABENAZINE Structure](CAS/20180713/GIF/718635-93-9.gif) |
| TETRABENAZINE Chemical Properties |
Melting point | 125 °C | Boiling point | 448.9±45.0 °C(Predicted) | density | 1.12±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO: ≥ 3.2 mg/mL (10.08 mM) | form | Solid | pka | 6.46±0.40(Predicted) | color | Light yellow to yellow |
| TETRABENAZINE Usage And Synthesis |
Uses | Tetrabenazine is a dopamine depleting medication for the treatment of chorea in Huntington’s disease. | Definition | ChEBI: 9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one is a benzoquinolizine that is 1,2,3,4,4a,9,10,10a-octahydrophenanthrene in which the carbon at position 10a is replaced by a nitrogen and which is substituted by an isobutyl group at position 2, an oxo group at position 3, and methoxy groups at positions 6 and 7. It is a benzoquinolizine, a cyclic ketone and a tertiary amino compound. |
| TETRABENAZINE Preparation Products And Raw materials |
Raw materials | N-[2-(3,4-dimethoxyphenyl)ethyl]formamide-->(2-Acetyl-4-Methylpentyl)triMethylaMMoniuM Iodide-->3-(N,N-Dimethylaminomethyl)-5-methyl-2-hexanone-->6,7-Dimethoxy-3,4-dihydroisoquinoline-->9,10-dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one-->6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride-->Methanol-->6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-->3,4-Dimethoxyphenethylamine |
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