| Company Name: |
China Kouting Group Limited
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| Tel: |
+86 (21) 5811-6473 5811-6475 |
| Email: |
sales@koutingchina.com |
| Products Intro: |
Product Name:BIBF1120
CAS:1160294-26-7
Purity:98%,99% HPLC Package:1g,10g,100g,1kg,10kg
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| Company Name: |
LETOPHARM LIMITED
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| Tel: |
+86-21-5821 5861 |
| Email: |
sales@letopharm.com |
| Products Intro: |
Product Name:BIBF1120
CAS:1160294-26-7
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| | (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Basic information |
| Product Name: | (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate | | Synonyms: | (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate;BIBF1120 7.4G;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-4-[methyl[2-(4-
methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester;2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid methyl ester;Vargatef Methyl ester;methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester | | CAS: | 1160294-26-7 | | MF: | C31H33N5O4 | | MW: | 539.62 | | EINECS: | | | Product Categories: | | | Mol File: | 1160294-26-7.mol |  |
| | (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties |
| Boiling point | 742.2±60.0 °C(Predicted) | | density | 1.284 | | pka | 11.06±0.20(Predicted) |
| | (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Usage And Synthesis |
| Definition | ChEBI: Nintedanib is a member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, a vascular endothelial growth factor receptor antagonist, a fibroblast growth factor receptor antagonist and an angiogenesis inhibitor. It is an aromatic ester, a methyl ester, a member of oxindoles, an enamine, an aromatic amine, an aromatic amide and a N-alkylpiperazine. It is a conjugate base of a nintedanib(1+). |
| | (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials |
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