| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Purity:affinity isolated antibody, lyophilized powder
|
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Email: |
|
| Products Intro: |
|
|
| | ANTI-CALCIUM CHANNEL (ALPHA1B SUBUNIT) (N-TYPE OF VOLTAGE-GATED CA2+ CHANNEL) Basic information |
| | ANTI-CALCIUM CHANNEL (ALPHA1B SUBUNIT) (N-TYPE OF VOLTAGE-GATED CA2+ CHANNEL) Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| | ANTI-CALCIUM CHANNEL (ALPHA1B SUBUNIT) (N-TYPE OF VOLTAGE-GATED CA2+ CHANNEL) Usage And Synthesis |
| Uses | Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit has been used in immunofluorescence analysis. | | General Description | The calcium channel, voltage-dependent, N type, α1B subunit (CACNA1B) or Cav2.2 gene consists of 47 exons and 46 introns, spanning 244kb. The gene is mapped to human chromosome 9q34. The encoded protein is a member of the voltage-gated calcium channel family. | | Biochem/physiol Actions | Calcium channel, voltage-dependent, N type, α1B subunit (CACNA1B) plays a vital role in regulation of trafficking and biophysical properties of voltage-gated calcium channels. Members of voltage-gated calcium channel family act as key transducers of cell surface membrane potential changes to local intracellular calcium transients that initiate various physiological events. The N-type voltage-gated calcium channels (VGCCs) expressed mainly in the neurons, facilitate neurotransmitter release at the sympathetic nerve terminals. CACNA1B is expressed on presynaptic nerve terminals of nociceptors control neurotransmitter release. |
| | ANTI-CALCIUM CHANNEL (ALPHA1B SUBUNIT) (N-TYPE OF VOLTAGE-GATED CA2+ CHANNEL) Preparation Products And Raw materials |
|