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| | 1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester Basic information |
| Product Name: | 1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester | | Synonyms: | 4-Amino-3,3-difluoro-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester;4-AMino-1-Boc-3,3-difluor...;4-AMino-1-Boc-3,3-difluoropiperidine;tert-butyl 4-aMino-3,3-difluoropiperidine-1-carboxylate;1-N-Boc-4-amino-3,3-difluoro-piperidine;tert-butyl 4-amino-3,3-difluoropiperidin;1-Boc-4-amino-3,3-difluoropiperidine | | CAS: | 1255666-48-8 | | MF: | C10H18F2N2O2 | | MW: | 236.26 | | EINECS: | | | Product Categories: | | | Mol File: | 1255666-48-8.mol |  |
| | 1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester Chemical Properties |
| Boiling point | 281.5±40.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 7.66±0.40(Predicted) |
| | 1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester Usage And Synthesis |
| Uses | 1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine is synthetic building block for pharmaceuticals. It can be obtained from N-Benzyl-β-alanine Ethyl Ester (B232975) which is used as a reagent in organic synthesis including that of dipivaloyloxyphenyl aminopropionate β-agonist prodrugs which are used in the treatment of psoriasis. N-Benzyl-β-alanine Ethyl Ester (B232975) is also used in the synthesis of N,N'-dithiobis(N-benzyl-β-alanine) dethyl ester, which is an important intermediate of insecticide OK-135, and in synthesis of spiropiperidine-based orexin-2 receptor (OX2R) antagonists. |
| | 1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester Preparation Products And Raw materials |
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