| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:16-(R)-Iloprost
CAS:74843-13-3
Package:10Mg,5Mg
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:16(R)-Iloprost
CAS:74843-13-3
Purity:98% Package:1G;10G;100G Remarks:Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:16(R)-Iloprost
CAS:74843-13-3
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | 16(R)-Iloprost Basic information |
| Product Name: | 16(R)-Iloprost | | Synonyms: | 16(R)-Iloprost;HIFJCPQKFCZDDL-GBSCXWAGSA-N;16(R)Iloprost,16(R) Iloprost;Pentanoic acid, 5-[hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene]-, [3aS-[2E,3aα,4α(1E,3R*,4S*),5β,6aα]]- (9CI);Parecoxib Impurity 87 | | CAS: | 74843-13-3 | | MF: | C22H32O4 | | MW: | 360.48708 | | EINECS: | | | Product Categories: | Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 74843-13-3.mol |  |
| | 16(R)-Iloprost Chemical Properties |
| Boiling point | 539.2±50.0 °C(Predicted) | | density | 1.210±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml | | pka | 4.77±0.10(Predicted) |
| | 16(R)-Iloprost Usage And Synthesis |
| Description | Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(R)-Iloprost inhibits platelet aggregation with an IC50 value of 65 nM. | | Uses | 16-(R)-Iloprost is the R-isomer of Iloprost (I267300), a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia. |
| | 16(R)-Iloprost Preparation Products And Raw materials |
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