Company Name: |
Biorbyt Ltd.
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Tel: |
+44 (0)1223 859 353 |
Email: |
info@biorbyt.com |
Products Intro: |
Product Name:Cox Polyclonal Antibody
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Company Name: |
Cayman Chemical Company
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Tel: |
(800) 364-9897 |
Email: |
cayman@caymanchem.com |
Products Intro: |
Product Name:COX Polyclonal Antibody Remarks:160103
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| COX Polyclonal Antibody Basic information |
| COX Polyclonal Antibody Chemical Properties |
| COX Polyclonal Antibody Usage And Synthesis |
Description | Cyclooxygenase catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2 COX-1 is constitutively expressed in almost all animal tissues and is involved in the homeostatic role of eicosanoids. Recent discoveries of the induction of cyclooxygenase biosynthesis by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of cyclooxygenase, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions. COX-1 and -2 are 70 and 72 kDa proteins, respectively. Both cyclooxygenases have been cloned from a variety of species including human, mouse, rat, and sheep. COX-1 isoform at the amino acid level, whereas the homology between COX-1 and COX-2 is only about 60%. |
| COX Polyclonal Antibody Preparation Products And Raw materials |
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