| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:JWH 250 N-(4-hydroxypentyl) metabolite
CAS:1427521-38-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:JWH 250 N-(4-hydroxypentyl) metabolite
CAS:1427521-38-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:JWH-250 4-Hydroxypentyl
CAS:1427521-38-7
Purity:NULL Package:100mg;10mg;51ml Remarks:NULL
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:JWH 250 N-(4-hydroxypentyl) metabolite
CAS:1427521-38-7
Purity:98% Package:10mg
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:JWH 250 N-(4-hydroxypentyl) metabolite
CAS:1427521-38-7
Package:>=98% Remarks:10939
|
|
| | JWH 250 N-(4-hydroxypentyl) metabolite Basic information |
| Product Name: | JWH 250 N-(4-hydroxypentyl) metabolite | | Synonyms: | JWH 250 N-(4-hydroxypentyl) metabolite;1-[1-(4-hydroxypentyl)indol-3-yl]-2-(2-methoxyphenyl)ethanone;JWH-250 N-4-hydroxypentyl;Ethanone, 1-[1-(4-hydroxypentyl)-1H-indol-3-yl]-2-(2-methoxyphenyl)- | | CAS: | 1427521-38-7 | | MF: | C22H25NO3 | | MW: | 351.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1427521-38-7.mol |  |
| | JWH 250 N-(4-hydroxypentyl) metabolite Chemical Properties |
| Boiling point | 541.7±40.0 °C(Predicted) | | density | 1.12±0.1 g/cm3(Predicted) | | solubility | DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml | | form | A crystalline solid | | pka | 15.20±0.20(Predicted) |
| | JWH 250 N-(4-hydroxypentyl) metabolite Usage And Synthesis |
| Description | JWH 250 is a synthetic cannabinoid (CB) which potently activates both CB1 and CB2 receptors (Ki values of 11 and 33 nM, respectively).1 It has been identified in herbal blends.2 JWH 250 N-(4-hydroxypentyl) metabolite is expected to be a cytochrome P450 phase I metabolite of JWH 250, detectable both in serum and urine.3,4,5 | | Uses | JWH-250 4-Hydroxypentyl is a urinary metabolite of JWH-250 (J211500) which acts as cannabinoid receptor 2 agonist. | | References | 1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles Bioorg. Med. Chem. Lett. 15(18),4110-4113(2005).
2. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3),109-115(2011).
3. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
4. Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS Anal. Bioanal. Chem. 386(5),1345-1355(2006).
5. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010). |
| | JWH 250 N-(4-hydroxypentyl) metabolite Preparation Products And Raw materials |
|