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Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-

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Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- Suppliers list
Company Name: SPIRO PHARMA  
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Products Intro: Product Name:Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-
CAS:1402612-58-1
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Products Intro: Product Name:KT195
CAS:1402612-58-1
Purity:98% Package:5mg;10mg;25mg
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Products Intro: Product Name:KT195
CAS:1402612-58-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: MedBioPharmaceutical Technology Inc  
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Products Intro: Product Name:Methanone, [4-(4-Methoxy[1,1-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-
CAS:1402612-58-1
Purity:98% Package:5mg; 25mg; 10mg Remarks:Medbio
Company Name: Energy Chemical  
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Email: marketing@energy-chemical.com
Products Intro: Product Name:KT195 >=98% (HPLC)
CAS:1402612-58-1
Purity:NULL Package:25mg;5mg Remarks:NULL
Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- Basic information
Product Name:Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-
Synonyms:Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-;[4-[4-(4-methoxyphenyl)phenyl]triazol-1-yl]-(2-phenylpiperidin-1-yl)methanone;KT-195 (ML 295);KT195 >=98% (HPLC);ML295 (KT195);4-(4'-methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-methanone
CAS:1402612-58-1
MF:C27H26N4O2
MW:438.52
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Mol File:1402612-58-1.mol
Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- Structure
Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- Chemical Properties
solubility DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.25 mg/ml
form A crystalline solid
Safety Information
MSDS Information
Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- Usage And Synthesis
DescriptionThe serine hydrolase known as α/β-hydrolase domain-containing protein 6 (ABHD6) hydrolyzes 2-arachidonoyl glycerol (2-AG; ) to regulate its availability at cannabinoid receptors. KT195 is a selective inhibitor of ABHD6 (IC50 = 10 nM) with negligible activity against other serine hydrolases such as DAGLβ. While it can be used as a probe to study ABHD6, it also has use as a negative control for studies of DAGLβ. By inactivating ABHD6, KT195 has been shown to induce a significant accumulation of 2-AG in Neuro2a cells. KT195 is also reported to reduce IL-1β secretion from lipopolysaccharide-treated macrophages.
Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- Preparation Products And Raw materials
Raw materials5-(4-bromophenyl)-1H-1,2,3-triazole
Tag:Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-(1402612-58-1) Related Product Information