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Product Name:Tie-2 Inhibitor 7
CAS:1020412-97-8
Purity:97%+ Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates
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| | Tie-2 Inhibitor 7 Basic information |
| Product Name: | Tie-2 Inhibitor 7 | | Synonyms: | Tie-2 Inhibitor 7;Tie inhibitor 7;Tie2 inhibitor;TIE2 INHIBITOR;TIE INHIBITOR 7;(S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid;3-Pyridinecarboxylic acid, 5-[4-[[[2-[[(1S)-1-cyclohexylethyl]amino]-2-oxoethyl][(4-methylphenoxy)carbonyl]amino]methyl]phenyl]-;Tie2 Inhibitor 7,Tie-2 Inhibitor 7 | | CAS: | 1020412-97-8 | | MF: | C31H35N3O5 | | MW: | 529.63 | | EINECS: | | | Product Categories: | | | Mol File: | 1020412-97-8.mol |  |
| | Tie-2 Inhibitor 7 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 14 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 1 mg/ml | | form | A crystalline solid |
| | Tie-2 Inhibitor 7 Usage And Synthesis |
| Description | Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization. |
| | Tie-2 Inhibitor 7 Preparation Products And Raw materials |
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