- Val-Cit-PAB-OH
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- $0.00 / 5g
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2024-03-29
- CAS:159857-79-1
- Min. Order: 5g
- Purity: >95.00%
- Supply Ability: 5g
- Val-cit-PAB-OH
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- $0.00 / 1KG
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2022-10-14
- CAS:159857-79-1
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1Ton
- Val-cit-PAB-OH
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- $1.00 / 1g
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2020-03-06
- CAS:159857-79-1
- Min. Order: 1g
- Purity: ≥98%
- Supply Ability: g/kg/Ton
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| | Val-cit-PAB-OH Basic information |
| Product Name: | Val-cit-PAB-OH | | Synonyms: | (S)-2-((R)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide;Val-cit-PAB-OH;L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide;EOS-61316;L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-;NH2-Val-Cit-PAB;(D)-VAL-CIT-PAB;al-Cit-PAB-OH | | CAS: | 159857-79-1 | | MF: | C18H29N5O4 | | MW: | 379.45 | | EINECS: | 826-617-2 | | Product Categories: | Linker;ADC LINKER;ADCs;ADC-Linkers | | Mol File: | 159857-79-1.mol |  |
| | Val-cit-PAB-OH Chemical Properties |
| Melting point | 168 °C(dec.) | | Boiling point | 715.0±60.0 °C(Predicted) | | density | 1.243±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml | | form | powder to crystal | | pka | 13.75±0.46(Predicted) | | color | White to Almost white |
| | Val-cit-PAB-OH Usage And Synthesis |
| Description | Val-Cit-PAB-OH is a peptide cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Cit will specifically be cleaved by Cathepsin B. | | Uses | Val-cit-PAB-OH acts as a reagent in the preparation of cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy, preparation of monomethylvaline derivative conjugates with ligands and antibodies for cancer treatment. |
| | Val-cit-PAB-OH Preparation Products And Raw materials |
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