| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Anti-ZMPSTE24 antibody produced in rabbit
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
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| | Anti-Zinc metalloproteinase Ste24 homolog antibody produced in rabbit Basic information |
| Product Name: | Anti-Zinc metalloproteinase Ste24 homolog antibody produced in rabbit | | Synonyms: | Anti-CAAX prenyl protease 1 homolog antibody produced in rabbit;Anti-FACE-1 antibody produced in rabbit;Anti-Farnesylated proteins-converting enzyme 1 antibody produced in rabbit;Anti-Prenyl protein-specific endoprotease 1 antibody produced in rabbit;Anti-Zinc metalloproteinase Ste24 homolog antibody produced in rabbit;Anti-ZMPSTE24 antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-Zinc metalloproteinase Ste24 homolog antibody produced in rabbit Structure]() |
| | Anti-Zinc metalloproteinase Ste24 homolog antibody produced in rabbit Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| | Anti-Zinc metalloproteinase Ste24 homolog antibody produced in rabbit Usage And Synthesis |
| Biological Activity | ZMPSTE24 (Zinc metallopeptidase STE24) is a nuclear membrane zinc metalloprotease. It possesses seven transmembrane α-helical barrel shaped structure with a large, water-filled, intramembrane chamber across periphery. It also has a zinc metalloprotease domain with the catalytic site facing into the intramembrane chamber. It endoproteolytically cleaves prelamin A, a component of the nuclear lamina intermediate filaments. The absence of this cleaving activity leads to the prelamin A accumulation in cells th at further causes laminopathies with premature aging disease progeria and metabolic disorders. Mutation in ZMPSTE24 also causes a rare autosomal recessive progeroid syndrome, mandibuloacral dysplasia (MAD). |
| | Anti-Zinc metalloproteinase Ste24 homolog antibody produced in rabbit Preparation Products And Raw materials |
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