Company Name: |
Alpha Biopharmaceuticals Co., Ltd
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Tel: |
0411-39042497 |
Email: |
sales@alphabiopharm.com |
Products Intro: |
Product Name:S-acetyl-PEG6-Tos CAS:1818294-25-5 Purity:98% HPLC Package:1g,5g,25g,100g,500g,1kg Remarks:F0984
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| S-acetyl-PEG6-Tos Basic information |
Product Name: | S-acetyl-PEG6-Tos | Synonyms: | S-acetyl-PEG6-Tos;Ethanethioic acid, S-[17-[[(4-methylphenyl)sulfonyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl] ester | CAS: | 1818294-25-5 | MF: | C21H34O9S2 | MW: | 494.62 | EINECS: | | Product Categories: | | Mol File: | 1818294-25-5.mol | ![S-acetyl-PEG6-Tos Structure](CAS/20210111/GIF/1818294-25-5.gif) |
| S-acetyl-PEG6-Tos Chemical Properties |
Boiling point | 591.0±50.0 °C(Predicted) | density | 1.202±0.06 g/cm3(Predicted) |
| S-acetyl-PEG6-Tos Usage And Synthesis |
Biological Activity | S-acetyl-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| S-acetyl-PEG6-Tos Preparation Products And Raw materials |
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