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Products Intro: |
Product Name:Taxine B CAS:1361-51-9 Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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guoyungurui
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Products Intro: |
Product Name:Valine Impurity 64 CAS:1361-51-9 Purity:95%+HPLC Package:10mg;25mg;50mg;100mg;200mg
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| 1361-50-8
Basic information |
Product Name: | 1361-50-8
| Synonyms: | Taxine B;1361-50-8;Benzenepropanoic acid, β-(dimethylamino)-, (3S,4aR,5S,6R,11R,12R,12aR)-11-(acetyloxy)-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-5,6,12-trihydroxy-9,12a,13,13-tetramethyl-4-methylene-8-oxo-6,10-methanobenzocyclodecen-3-yl ester, (βS)-;Valine Impurity 64 | CAS: | 1361-51-9 | MF: | C33H45NO8 | MW: | 583.7123 | EINECS: | | Product Categories: | | Mol File: | 1361-51-9.mol | ![1361-50-8
Structure](CAS/20180808/GIF/1361-51-9.gif) |
| 1361-50-8
Chemical Properties |
Melting point | l13-5°C (approx.) | Boiling point | 676.9±55.0 °C(Predicted) | density | 1.25±0.1 g/cm3(Predicted) | solubility | Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) | form | Solid | pka | 12.63±0.70(Predicted) | color | White to Off-White | Stability: | Hygroscopic |
| 1361-50-8
Usage And Synthesis |
Description | A constituent of Taxus baccata, this alkaloid is amorphous and has [α]20D + 119°
(CHC13). The hydrochloride is also amorphous with no definite melting point.
The nitrate, however, can be crystallized from Et20-isopropanol, m.p. 190°C.
The base yields a diacetyl derivative which, although amorphous when obtained
from aqueous solution, m.p. 92°C, forms colourless crystals from EtOH, m.p.
161.5°C. This latter base has [α]20Do + 106.7° (c 2.0, CHC1 3) and gives a crystalline
hydrochloride from EtOH containing solvent of crystallization, m.p. 168-l70°C;
nitrate as colourless needles or plates from EtOH, m.p. 141.5°C and the
methiodide, m.p. 197°C. The structure of the alkaloid is that of Taxine I (q.v.)
minus two acetyl groups. | Uses | Taxine B is a toxic pyrrolizidine alkaloid obtained from rhodadendron and ragwort plants decomposition. An impurity in the biosynthesis of Paclitaxel (P132500) | References | Harrison, Scrowston, Lythgoe., 1. Chern. Soc., C, 1933 (1966) |
| 1361-50-8
Preparation Products And Raw materials |
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