Fingolimod Impurity 8

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CAS:162358-96-5
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Fingolimod Impurity 8 Basic information
Product Name:Fingolimod Impurity 8
Synonyms:Fingolimod Impurity 7;2-octylphenethyl iodide;1-?(2-?Iodoethyl)?-?2-?octylbenzene;Benzene, 1-(2-iodoethyl)-2-octyl-
CAS:162358-96-5
MF:C16H25I
MW:344.27
EINECS:
Product Categories:
Mol File:162358-96-5.mol
Fingolimod Impurity 8 Structure
Fingolimod Impurity 8 Chemical Properties
Boiling point 363.2±21.0 °C(Predicted)
density 1.261±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
Fingolimod Impurity 8 Usage And Synthesis
Uses1-?(2-?Iodoethyl)?-?2-?octylbenzene is an impurity of Fingloimod (F805000), also known as FTY720. FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
Fingolimod Impurity 8 Preparation Products And Raw materials
Tag:Fingolimod Impurity 8(162358-96-5) Related Product Information
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