| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:17(R)-Resolvin D1 methyl ester
CAS:937738-64-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:17(R)-Resolvin D1 methyl ester
CAS:937738-64-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:17(R)-Resolvin D1 methyl ester
CAS:937738-64-2
Purity:95% Package:10μg;25μg;50μg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:17(R)-Resolvin D1 methyl ester
CAS:937738-64-2
Purity:0 Package:50mg;10mg
|
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| | 17(R)-Resolvin D1 methyl ester Basic information |
| Product Name: | 17(R)-Resolvin D1 methyl ester | | Synonyms: | 17(R)-Resolvin D1 methyl ester;WUKVAFWBFGABJN-PFYFFMTHSA-N;4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, methyl ester, (4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)- | | CAS: | 937738-64-2 | | MF: | C23H34O5 | | MW: | 390.51 | | EINECS: | | | Product Categories: | | | Mol File: | 937738-64-2.mol |  |
| | 17(R)-Resolvin D1 methyl ester Chemical Properties |
| Boiling point | 562.1±50.0 °C(Predicted) | | density | 1.064±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml | | pka | 13.33±0.20(Predicted) |
| | 17(R)-Resolvin D1 methyl ester Usage And Synthesis |
| Description | 17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). 17(R)-RvD1 exhibits a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with maximal inhibition of ~35% at a 100 ng dose. In contrast to RvD1, the aspirin-triggered form resists rapid inactivation by eicosanoid oxidoreductases. 17(R)-RvD1 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid. |
| | 17(R)-Resolvin D1 methyl ester Preparation Products And Raw materials |
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