| Company Name: |
Jilin Chinese Academy of Sciences-yanshen Technology |
| Tel: |
+undefined18143011203 |
| Email: |
info@chemextension.com |
| Products Intro: |
Product Name:32-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-oic acid
CAS:2250056-53-0
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
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| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
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| Tel: |
010-60605840 15801484223; |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:HO-PEG10-CH2COOH
CAS:2250056-53-0
Purity:95% Package:100mg;250mg;1g
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:HO-PEG10-CH2COOH
CAS:2250056-53-0
Package:5mg/RMB 208;10mg/RMB 293;2mg/RMB 142
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| | HO-PEG10-CH2COOH Basic information |
| | HO-PEG10-CH2COOH Chemical Properties |
| Boiling point | 604.7±50.0 °C(Predicted) | | density | 1.154±0.06 g/cm3(Predicted) | | pka | 3.39±0.10(Predicted) | | form | Oil | | color | Colorless to light yellow |
| | HO-PEG10-CH2COOH Usage And Synthesis |
| Biological Activity | HO-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | HO-PEG10-CH2COOH Preparation Products And Raw materials |
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