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LYN-1604

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LYN-1604 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:LYN-1604
CAS:2088939-99-3
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:LYN-1604
CAS:2088939-99-3
Purity:MIn98%HPLC/LC Package:1KG;1USD
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:LYN-1604
CAS:2088939-99-3
Purity:98% Package:5mg Remarks:V3195
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:LYN-1604；LYN1604;LYN 1604
CAS:2088939-99-3
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:LYN-1604 hydrochloride
CAS:2088939-99-3
Purity:>=98% Package:$105.9/1mg;$362.9/5mg;$593.9/10mg;$1329.9/25mg;$2393.9/50mg;$3433.9/100mg;Bulk p Remarks:98%

LYN-1604 manufacturers

  • LYN-1604
  • LYN-1604 pictures
  • $106.00 / 1mg
  • 2024-11-19
  • CAS:2088939-99-3
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
  • LYN-1604
  • LYN-1604 pictures
  • $1.00 / 1KG
  • 2024-10-22
  • CAS:2088939-99-3
  • Min. Order: 1KG
  • Purity: MIn98%HPLC/LC
  • Supply Ability: 100KGS
LYN-1604 Basic information
Product Name:LYN-1604
Synonyms:LYN-1604;LYN-1604 Hcl;CS-2610;CS-2635;LYN-1604;LYN 1604;LYN1604;LYN1604;LYN 1604;Ethanone, 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-;LYN-1604 2HCl
CAS:2088939-99-3
MF:C33H43Cl2N3O2
MW:584.62
EINECS:
Product Categories:
Mol File:2088939-99-3.mol
LYN-1604 Structure
LYN-1604 Chemical Properties
Boiling point 670.9±55.0 °C(Predicted)
density 1.168±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form A crystalline solid
pka8.03±0.50(Predicted)
Safety Information
MSDS Information
LYN-1604 Usage And Synthesis
DescriptionLYN-1604 is an activator of unc-51-like kinase 1 (ULK1; EC50 = 18.94 nM). It increases Beclin 1, LC3-II, and total LC3 protein levels and reduces levels of p62 in human MDA-MB-231 triple-negative breast cancer (TNBC) cells in a concentration-dependent manner, indicating an increase in autophagy. It also increases the cleavage of the pro-apoptotic protein caspase-3. LYN-1604 decreases the viability of MDA-MB-231 cells in vitro (IC50 = 1.66 μM), an effect that can be reversed by the autophagy inhibitor 3-methyladenine (3-MA; ). LYN-1604 (25, 50, and 100 mg/kg) reduces tumor growth in an MDA-MB-231 mouse xenograft model.
LYN-1604 Preparation Products And Raw materials
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