- DLIN-KC2-DMA
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- $1.00 / 1KG
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2020-02-02
- CAS:1190197-97-7
- Min. Order: 1KG
- Purity: 99%HPLC
- Supply Ability: 100KG
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| DLin-KC2-DMA Basic information |
Product Name: | DLin-KC2-DMA | Synonyms: | DLin-KC2-DMA;1,3-Dioxolane-4-ethanamine, N,N-dimethyl-2,2-di-(9Z,12Z)-9,12-octadecadien-1-yl-;2-(2,2-Di((9Z,12Z)-octadeca-9,12-dien-1-yl)-1,3-dioxolan-4-yl)-N,N-dimethylethanamine;2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine;DLin-KC-2-DMA,inhibit,Inhibitor,DLin KC2 DMA,DLinKC2DMA;KC2 | CAS: | 1190197-97-7 | MF: | C43H79NO2 | MW: | 642.09 | EINECS: | | Product Categories: | | Mol File: | 1190197-97-7.mol | ![DLin-KC2-DMA Structure](CAS/20200515/GIF/1190197-97-7.gif) |
| DLin-KC2-DMA Chemical Properties |
Boiling point | 668.1±40.0 °C(Predicted) | density | 0.885±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C,unstable in solution, ready to use. | solubility | Soluble in Ethanol, DMSO, DMF | pka | 9.32±0.28(Predicted) | form | Liquid | color | Colorless to light yellow | InChIKey | LRFJOIPOPUJUMI-MNMREVDWSA-N | SMILES | O1CC(CCN(C)C)OC1(CCCCCCCCC=CCC=CCCCCC)CCCCCCCC/C=C\C/C=C\CCCCC |
| DLin-KC2-DMA Usage And Synthesis |
Description | DLin-KC2-DMA is a useful ionizable lipid for siRNA delivery. It was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates. |
| DLin-KC2-DMA Preparation Products And Raw materials |
Raw materials | 6,9,28,31-Heptatriacontatetraen-19-one, (6Z,9Z,28Z,31Z)--->6,9,28,31-Heptatriacontatetraen-19-ol, 19-formate, (6Z,9Z,28Z,31Z)--->6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)--->Dimethylamine |
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