- DLIN-KC2-DMA
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- $1.00 / 1KG
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2020-02-02
- CAS:1190197-97-7
- Min. Order: 1KG
- Purity: 99%HPLC
- Supply Ability: 100KG
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| | DLin-KC2-DMA Basic information |
| Product Name: | DLin-KC2-DMA | | Synonyms: | DLin-KC2-DMA;1,3-Dioxolane-4-ethanamine, N,N-dimethyl-2,2-di-(9Z,12Z)-9,12-octadecadien-1-yl-;2-(2,2-Di((9Z,12Z)-octadeca-9,12-dien-1-yl)-1,3-dioxolan-4-yl)-N,N-dimethylethanamine;2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine;DLin-KC-2-DMA,inhibit,Inhibitor,DLin KC2 DMA,DLinKC2DMA;KC2 | | CAS: | 1190197-97-7 | | MF: | C43H79NO2 | | MW: | 642.09 | | EINECS: | | | Product Categories: | | | Mol File: | 1190197-97-7.mol |  |
| | DLin-KC2-DMA Chemical Properties |
| Boiling point | 668.1±40.0 °C(Predicted) | | density | 0.885±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C,unstable in solution, ready to use. | | solubility | Soluble in Ethanol, DMSO, DMF | | pka | 9.32±0.28(Predicted) | | form | Liquid | | color | Colorless to light yellow | | InChIKey | LRFJOIPOPUJUMI-MNMREVDWSA-N | | SMILES | O1CC(CCN(C)C)OC1(CCCCCCCCC=CCC=CCCCCC)CCCCCCCC/C=C\C/C=C\CCCCC |
| | DLin-KC2-DMA Usage And Synthesis |
| Description | DLin-KC2-DMA is a useful ionizable lipid for siRNA delivery. It was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates. |
| | DLin-KC2-DMA Preparation Products And Raw materials |
| Raw materials | 6,9,28,31-Heptatriacontatetraen-19-one, (6Z,9Z,28Z,31Z)--->6,9,28,31-Heptatriacontatetraen-19-ol, 19-formate, (6Z,9Z,28Z,31Z)--->6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)--->Dimethylamine |
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