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Hefei Molake Biotechnology Co., Ltd.
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Product Name:Rosuvastatin-d6 Sodium Salt CAS:2070009-41-3 Purity:98% Package:10mg,100mg,1g,10g
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Product Name:Rosuvastatin-d6 sodium salt CAS:2070009-41-3 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Cato Research Chemicals Inc.
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020-81215950 4000-868-328 |
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Product Name:Rosuvastatin-d6 Sodium Salt CAS:2070009-41-3 Purity:95%(HPLC) Package:10mg;25mg;50mg;100mg
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| sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Basic information |
Product Name: | sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate | Synonyms: | sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate;(3R,5S,E)-7-(4-(4-fluorophenyl)-2-(N-methylmethylsulfonamido)-6-(propan-2-yl-1,1,1,3,3,3-d6)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate,monosodiumsalt;Rosuvastatin Sodium D6Q: What is
Rosuvastatin Sodium D6 Q: What is the CAS Number of
Rosuvastatin Sodium D6 Q: What is the storage condition of
Rosuvastatin Sodium D6 Q: What are the applications of
Rosuvastatin Sodium D6;Rosuvastatin Sodium Salt-D6;Antipyrine Impurity 15 | CAS: | 2070009-41-3 | MF: | C22H29FN3NaO6S | MW: | 505.54 | EINECS: | | Product Categories: | | Mol File: | 2070009-41-3.mol | ![sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Structure](CAS/20211123/GIF/2070009-41-3.gif) |
| sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Chemical Properties |
storage temp. | Store at 4°C | solubility | Methanol: Soluble | form | A solid |
| sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Usage And Synthesis |
Biological Activity | Rosuvastatin-d6 is intended for use as an internal standard for the quantification of rosuvastatin by GC- or LC-MS. Rosuvastatin is an HMG-CoA reductase inhibitor (IC50 = 5 nM).1,2 It is a fully-synthetic inhibitor that is designed to maximize the points of contact with, and inhibition of, HMG-CoA reductase.1 Formulations containing rosuvastatin reduce low-density lipoprotein and C-reactive protein and increase high-density lipoprotein in humans.3,4 | References | 1.Istvan, E.S., and Deisenhofer, J.Structural mechanism for statin inhibition of HMG-CoA reductaseScience292(5519)1160-1164(2001)
2.Tobert, J.A.Lovastatin and beyond: The history of the HMG-CoA reductase inhibitorsNat. Rev. Drug Discov.2(7)517-526(2003)
3.Asztalos, B.F., Maulf, F.L., Dallal, G.E., et al.Comparison of the effects of high doses of Rosuvastatin versus Atorvastatin on the subpopulations of high-density lipoproteinsAm. J. Cardiol.99(5)681-685(2007)
4.Rubba, P., Marotta, G., and Gentile, M.Efficacy and safety of rosuvastatin in the management of dyslipidemiaVasc. Health Risk Manag.5(1)343-352(2009) |
| sodium:(E,3R,5S)-7-[4-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate Preparation Products And Raw materials |
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