| Company Name: |
Shenzhen Botel Biotechnology Co. Ltd.
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| Tel: |
0755-22202135 13316968096 |
| Email: |
1979313431@qq.com |
| Products Intro: |
Product Name:Chlorpromazine 7-Hydroxy Impurity
CAS:51938-11-5
Purity:98% HPLC Package:10mg;25mg;50mg
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:7-Hydroxy Chlorpromazine Hydrochloride
CAS:51938-11-5
Purity:NULL Package:2.5mg;25mg Remarks:NULL
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| Company Name: |
ChemeGen 中国
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:7-hydroxy Chlorpromazine hydrochloride
CAS:51938-11-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | OTIORHLXOLCOAV-UHFFFAOYSA-N Basic information |
| Product Name: | OTIORHLXOLCOAV-UHFFFAOYSA-N | | Synonyms: | OTIORHLXOLCOAV-UHFFFAOYSA-N;Chlorpromazine 7-Hydroxy Impurity;7-Hydroxy-chlorpromazine hydrochloride salt;10H-Phenothiazin-3-ol, 8-chloro-10-[3-(dimethylamino)propyl]-,monohydrochloride | | CAS: | 51938-11-5 | | MF: | C17H20Cl2N2OS | | MW: | 371.32 | | EINECS: | | | Product Categories: | | | Mol File: | 51938-11-5.mol |  |
| | OTIORHLXOLCOAV-UHFFFAOYSA-N Chemical Properties |
| storage temp. | -20°C | | solubility | Methanol: slightly soluble | | form | A solid | | Stability: | Hygroscopic |
| | OTIORHLXOLCOAV-UHFFFAOYSA-N Usage And Synthesis |
| Uses | 7-Hydroxychlorpromazine is the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750). | | Biological Activity | 7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .1 In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.2 | | References | 1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977)
2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974) |
| | OTIORHLXOLCOAV-UHFFFAOYSA-N Preparation Products And Raw materials |
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