Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:S1QEL CAS:897613-29-5 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| N'-(3-acetamidophenyl)-N-[2-[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]ethyl]oxamide Basic information |
| N'-(3-acetamidophenyl)-N-[2-[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]ethyl]oxamide Chemical Properties |
density | 1.300±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.33 mg/ml; DMSO: 2 mg/ml | form | A crystalline solid | pka | 11.19±0.70(Predicted) |
| N'-(3-acetamidophenyl)-N-[2-[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]ethyl]oxamide Usage And Synthesis |
Description | S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation. It diminishes endogenous oxidative damage in primary astrocytes, reduces stress-induced signaling in a cardiomyocyte cell model, and protects against ischemia-reperfusion injury in perfused mouse heart. |
| N'-(3-acetamidophenyl)-N-[2-[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]ethyl]oxamide Preparation Products And Raw materials |
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