3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid manufacturers
- Poloppin
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- $65.00 / 1mg
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2024-10-28
- CAS:683808-78-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Basic information |
| 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Chemical Properties |
Boiling point | 536.7±50.0 °C(Predicted) | density | 1.45±0.1 g/cm3(Predicted) | storage temp. | 2-8°C | solubility | DMSO: 2mg/mL, clear | pka | 4.62±0.10(Predicted) | form | powder | color | white to beige |
| 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Usage And Synthesis |
Description | Poloppin is a modulator of protein-protein interactions of the mitotic polo-like kinases. It acts by targeting mutant KRAS, working synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells. |
| 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Preparation Products And Raw materials |
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