Log in | Join Free | china | japan | germany

(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE

Request For Quotation
(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:GNE 5729
CAS:2026635-66-3
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:GNE 5729
CAS:2026635-66-3
Purity:99% Package:$780.9/5mg;$1250.9/10mg;Bulk package Remarks:99%
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:GNE 5729;GNE 5729
CAS:2026635-66-3
Purity:98% Package:5 mg
Company Name: Shanghai?Medlife?Pharm-Tech?Co.,?Ltd  
Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Products Intro: Product Name:GNE 5729
CAS:2026635-66-3
Purity:>=99% Package:5mg;10mg;100mg;50mg
Company Name: AstaTech, Inc  
Tel: (215) 785 3197
Email: sales@astatechinc.com
Products Intro: Product Name:(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE
CAS:2026635-66-3
Purity:0.95 Package:1g
(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE Basic information
Product Name:(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE
Synonyms:(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE;GNE 5729;Cyclopropanecarbonitrile, 2-[7-chloro-2-[[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl]-4-oxo-4H-pyrido[1,2-a]pyrimidin-6-yl]-, (1R,2R)-
CAS:2026635-66-3
MF:C17H10Cl2F3N5O
MW:428.2
EINECS:
Product Categories:
Mol File:2026635-66-3.mol
(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE Structure
(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE Chemical Properties
Boiling point 527.6±60.0 °C(Predicted)
density 1.71±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka0.89±0.70(Predicted)
form Solid
color White to yellow
Safety Information
MSDS Information
(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE Usage And Synthesis
DescriptionGNE-5729 is a potent and selective NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. GNE-5729 had a very selective profile against various off-target ion channels with greater than a 100-fold selectivity over other NMDAR subtypes and greater than a 1000-fold selectivity over AMPAR. The improved pharmacokinetic profile and AMPAR selectivity make GNE-5729 a superior tool compound compare to GNE-0723 for testing the efficacy and safety of GluN2A potentiation.
(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE Preparation Products And Raw materials
Tag:(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE(2026635-66-3) Related Product Information