| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-RIP3
Purity:~ 1.0mg/mL, affinity isolated antibody, buffered aqueous sol Package:100μg Remarks:R4277
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| | ANTI-RECEPTOR INTERACTING PROTEIN 3 Basic information |
| Product Name: | ANTI-RECEPTOR INTERACTING PROTEIN 3 | | Synonyms: | ANTI-RECEPTOR INTERACTING PROTEIN 3;ANTI-RECEPTOR-INTERACTING SERINE/THREONINE PROTEIN KINASE 3 (HUMAN);ANTI-RIP3;ANTI-RIP-LIKE PROTEIN KINASE 3 (HUMAN);ANTI-RIP3 (HUMAN);ANTI-RAT RIP3;ANTI-RAT RIP3 POLYCLONAL ANTIBODY;Anti-RIP3 antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-RECEPTOR INTERACTING PROTEIN 3 Structure]() |
| | ANTI-RECEPTOR INTERACTING PROTEIN 3 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-RECEPTOR INTERACTING PROTEIN 3 Usage And Synthesis |
| Uses | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper) | | Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | MPRIP (Myosin phosphatase Rho interacting protein) is a serine/threonine protein kinase mapped on human chromosome 17p11.2. It is localized to actin-myosin stress fibers. | | Biochem/physiol Actions | MPRIP (Myosin phosphatase Rho interacting protein) controls the switch from apoptosis to necroptosis. It is associated with several diseases. MPRIP functions as a component of the myosin phosphatase complex and combines with the myosin binding subunit of myosin phosphatase and RhoA. Absence or deficiency of MPRIP protects hepatocytes from ethanol-mediated injury, prevents cerulean-activated acute necrotizing pancreatitis, suppresses photoreceptor and cone cell death, and improves macrophage necrosis in advanced atherosclerosis lesions. |
| | ANTI-RECEPTOR INTERACTING PROTEIN 3 Preparation Products And Raw materials |
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