| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-CCL2 antibody produced in rabbit
Purity:Prestige Antibodies(R) Powered by Atlas Antibodies, affinity Package:100UL Remarks:HPA019163-100UL
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| | ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Basic information |
| Product Name: | ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 | | Synonyms: | ANTI-MONOCYTE CHEMOTATIC AND ACTIVATING FACTOR;ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1;ANTI-MCAF;ANTI-MCP-1;ANTI-MCP-1/ACTIVATING FACTOR, HUMAN;Anti-Monocyte Chemotactic Protein 1 antibody produced in goat;Anti-CCL2;Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Structure]() |
| | ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder |
| | ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Usage And Synthesis |
| Uses | Monoclonal anti-Monocyte Chemotactic Protein-1 antibody can be used in western blotting. | | Uses | Anti-CCL2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | C-C motif chemokine ligand 2 (CCL2) gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. (provided by RefSeq).CCL2 is a pro-inflammatory cytokine. It belongs to the family of CC-type chemokines, which can be produced by almost every cells. | | Biochem/physiol Actions | C-C motif chemokine ligand 2 (CCL2) plays a critical role in the development of allergic inflammatory reactions by employing immune cells, that is linked to autoimmune diseases. It binds to CC chemokine receptor 2 (CCR2) and regulates monocyte chemotaxis and T-lymphocyte differentiation. The protein recruits monocytes to liver. It is involved in macrophage fusion and foreign body giant cell formation. |
| | ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Preparation Products And Raw materials |
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