人参皂甙 Rc
中文名称 | 人参皂甙 Rc |
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中文同义词 | 人参皂苷RC(人参皂甙RC);GINSENOSIDE RC 人参皂苷RC;人参皂苷RC;人参皂甙RC;人参皂苷 RC, 来源于人参;人叁皂甙RC;人参皂荚RB1;人参皂荚RC |
英文名称 | Ginsenoside Rc |
英文同义词 | Ginsenoside Rc, froM Panax ginseng;NSC 310104;20-[(6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranosyl)oxy]-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside;GINSENOSIDE FROM GINSENG ROOT (PANAX*QUI NQUEFOLIUM;20-[(6-O-alpha-L-Arabinofuranosyl-beta-D-glucopyranosyl)oxy]-12b-hydroxydammar-24-en-3b-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside;GINSENOSIDE RC WITH HPLC;arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-;glucopyranosyl- |
CAS号 | 11021-14-0 |
分子式 | C53H90O22 |
分子量 | 1079.27 |
EINECS号 | 234-253-5 |
植物来源 | 人参 |
相关类别 | 植提;小分子抑制剂,天然产物;有机硼化合物;小分子抑制剂;中药对照品;标准品;对照品,标准品;分析标准品;植物提取物;对照品;植提标准品;中药标准品;化学试剂;分析试剂标准品;生化试剂-其他化学试剂;标准品-中药标准品;标准品,对照品;三萜;Saponins;Biochemicals Found in Plants;Isoprenoid/terpenoid;Nutrition Research;Ginsenoside series;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;标准品 -中药标准品;分析试剂-对照品;标准品-对照品;生物化工;原料 |
Mol文件 | 11021-14-0.mol |
结构式 | ![]() |
人参皂甙 Rc 性质
熔点 | 199~201℃ |
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沸点 | 1128.3±65.0 °C(Predicted) |
密度 | 1.42±0.1 g/cm3(Predicted) |
储存条件 | Sealed in dry,2-8°C |
溶解度 | DMSO(微量)、甲醇(微量)、吡啶(微量) |
形态 | 固体 |
酸度系数(pKa) | 12.85±0.70(Predicted) |
颜色 | 白色至浅黄色 |
稳定性 | 吸湿性 |
LogP | 5.100 (est) |
CAS 数据库 | 11021-14-0(CAS DataBase Reference) |
TNF-α
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IL-1β
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Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances γ-aminobutyric acid (GABA) receptor A (GABA A )-mediated ion channel currents. Ginsenoside Rc enhances GABA-mediated ion currents in oocytes expressing the GABA A receptor. Ginsenoside Rc significantly inhibits the expression of macrophage-derived cytokines, such as TNF-α and IL-1β. Ginsenoside Rc also markedly suppresses the activation of TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling in activated RAW264.7 macrophages, human synovial cells, and HEK293 cells. Ginsenoside Rc exerts its anti-inflammatory actions by suppressing TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling. Ginsenoside Rc suppresses the nuclear translocation of phospho-ATF-2 and phospho-FRA-1, whereas the translocation of p65 at its peak time points (30 and 60 min) is not decreased by Ginsenoside Rc treatment. Ginsenoside Rc regulates the expression of the proinflammatory cytokine TNF-α, which is produced by macrophages, by suppressing AP-1 activation.
提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-N0042 | 人参皂甙 Rc Ginsenoside Rc | 11021-14-0 | 5mg | 650元 |
2024/08/19 | HY-N0042 | 人参皂甙 Rc Ginsenoside Rc | 11021-14-0 | 10mg | 1100元 |