| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:CCG-224406
CAS:1870843-22-3
Purity:98% Package:5 mg
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| | CCG224406) Basic information |
| Product Name: | CCG224406) | | Synonyms: | CCG-224406
(CCG 224406;CCG224406);5-Pyrimidinecarboxamide, 4-[3-[[[(2,6-dimethoxyphenyl)methyl]amino]carbonyl]-4-fluorophenyl]-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo- | | CAS: | 1870843-22-3 | | MF: | C29H27FN6O5 | | MW: | 558.56 | | EINECS: | | | Product Categories: | | | Mol File: | 1870843-22-3.mol |  |
| | CCG224406) Chemical Properties |
| Boiling point | 802.0±65.0 °C(Predicted) | | density | 1.375±0.06 g/cm3(Predicted) | | pka | 11.09±0.70(Predicted) |
| | CCG224406) Usage And Synthesis |
| Description | CCG-22440 is a Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitor. CCG-224406 had an IC50 for GRK2 of 130 nM, greater than 700-fold selectivity over other GRK subfamilies, and no detectable inhibition of ROCK1. G protein-coupled receptors (GPCRs) are central to many physiological processes. Regulation of this superfamily of receptors is controlled by GPCR kinases (GRKs), some of which have been implicated in heart failure. |
| | CCG224406) Preparation Products And Raw materials |
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