[Met5]-Enkephalin, amide TFA
| 中文名称 | [Met5]-Enkephalin, amide TFA |
|---|---|
| 中文同义词 | |
| 英文名称 | [Met5]-Enkephalin, amide TFA |
| 英文同义词 | [Met5]-Enkephalin, amide TFA;[Met5] Enkephalin, amide TFA,[Met-5]-Enkephalin, amide TFA,[Met5]Enkephalin, amide TFA;5-Methionine-enkephalin amide (TFA) |
| CAS号 | 2918768-28-0 |
| 分子式 | C??H??F?N?O?S |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | Mol File |
| 结构式 |
[Met5]-Enkephalin, amide TFA 性质
| 形态 | 固体 |
|---|---|
| 颜色 | 白色至米白色 |
[Met5]-Enkephalin, amide TFA 是一种 δ 和 ζ 阿片受体 (opioid receptor) 激动剂。
δ and ζ opioid receptor
[Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC 50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine.