Thalidomide-linker 6 manufacturers
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| | Thalidomide-linker 6 Basic information |
| Product Name: | Thalidomide-linker 6 | | Synonyms: | Thalidomide-linker 6;-ether-alkylC2-amine;4-(2-aminoethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;Thalidomide-O-C2-NH2 hydrochloride;Thalidomide 4'-ether-alkylC2-amine;Thalidomide 4'-ether-alkylC2-amine (hydrochloride);Thalidomide-linker 6 hydrochloride;halidomide-linker 6 | | CAS: | 2341840-99-9 | | MF: | C15H16ClN3O5 | | MW: | 353.76 | | EINECS: | | | Product Categories: | | | Mol File: | 2341840-99-9.mol |  |
| | Thalidomide-linker 6 Chemical Properties |
| solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | Thalidomide-linker 6 Usage And Synthesis |
| Uses | Thalidomide-4-O-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | | IC 50 | Cereblon | | storage | Store at -20°C | | References | [1] Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996;93(15):7552‐7556. DOI:10.1073/pnas.93.15.7552 |
| | Thalidomide-linker 6 Preparation Products And Raw materials |
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Tag:Thalidomide-linker 6(2341840-99-9)
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Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Thalidomide-O-C6-NH2 TFA
Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
1H-Isoindole-1,3(2H)-dione, 4-[(10-aminodecyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-
Propanoic acid, 3-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
1H-Isoindole-1,3(2H)-dione, 4-[(7-aminoheptyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-
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