| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:TDZD-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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TDZD-8 manufacturers
- TDZD-8
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- $1.00 / 1g
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2019-12-24
- CAS:7036-89-5
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 20kg
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| Product Name: | TDZD-8 | | Synonyms: | 4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE;GSK-3BETA INHIBITOR I;TDZD-8 | | CAS: | | | MF: | C10H10N2O2S | | MW: | 222.26 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | TDZD-8 Chemical Properties |
| Melting point | 63-64.4 °C | | storage temp. | 2-8°C | | solubility | DMSO: 18 mg/mL | | form | needles | | color | white |
| Hazard Codes | Xi | | Risk Statements | 43 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | TDZD-8 Usage And Synthesis |
| Uses | A thiadiazolidinone (TDZD) analog that acts as a highly selective, non-ATP competitive inhibitor of GSK-3 | | Uses | Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3? ( IC50 =2nM). Binds to the active site of GSK-3?. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM). |
| | TDZD-8 Preparation Products And Raw materials |
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