| Company Name: |
ShangHai Biochempartner Co.,Ltd
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| Tel: |
17754423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:Tolvaptan Impurity 22
CAS:2055602-83-8
Purity:98% HPLC LCMS Package:1G;100G
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| | BAY-1797 Basic information |
| Product Name: | BAY-1797 | | Synonyms: | BAY-1797;paw,ion,inhibit,anti-inflammatory,CFA,Complete,P2XRs,BAY-1797,Freund’s,selective,channel,P2X Receptor,inflamed,Inhibitor,BAY1797,Adjuvant,BAY 1797,P2X,anti-nociceptive;Benzeneacetamide, N-[3-(aminosulfonyl)-4-(3-chlorophenoxy)phenyl]- | | CAS: | 2055602-83-8 | | MF: | C20H17ClN2O4S | | MW: | 416.88 | | EINECS: | | | Product Categories: | | | Mol File: | 2055602-83-8.mol |  |
| | BAY-1797 Chemical Properties |
| density | 1.414±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO (>25 mg/ml) | | form | solid | | pka | 9.84±0.60(Predicted) | | color | Pale brown | | Stability: | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| | BAY-1797 Usage And Synthesis |
| Description | BAY-1797 (2055602-83-8) is a selective P2X4 receptor antagonist (IC50 = 211 nM HEK cellular assay; P2X4 calcium influx based assays – hIC50 = 108 nM, mIC50 = 112 nM, rIC50 = 233 nM).1 Displayed antinociceptive and anti-inflammatory effects in mouse CFA inflammatory pain models. | | storage | Store at -20°C | | References | Werner et al. (2019) Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile; J. Med. Chem. 62 11194 |
| | BAY-1797 Preparation Products And Raw materials |
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