| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd. Gold
|
| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Siltuximab
Purity:>95%;1mg/ml Package:200ug;500ug;1mg
|
| Company Name: |
ShangHai Biochempartner Co.,Ltd
|
| Tel: |
17754423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:Siltuximab
CAS:541502-14-1
Purity:95% Package:100ug;500ug;1mg
|
| Company Name: |
Guangzhou Hongyuan Chemical Co.,Ltd
|
| Tel: |
15817493340 |
| Email: |
981810490@qq.com |
| Products Intro: |
Product Name:Siltuximab
CAS:541502-14-1
Purity:95% Package:1mg;1g;100g
|
|
| | Siltuximab Basic information |
| Product Name: | Siltuximab | | Synonyms: | Siltuximab;Research Grade Siltuximab(DHC15801);Siltuximab (anti-IL-6);CNTO-328 | | CAS: | 541502-14-1 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Siltuximab Structure]() |
| | Siltuximab Chemical Properties |
| storage temp. | Store at -20°C | | form | Liquid | | color | Colorless to light yellow |
| | Siltuximab Usage And Synthesis |
| Uses | Siltuximab it is used for cancer treatment using anti-ICOS antibody if patient has low peripheral T cell receptor clonality. | | Clinical Use | Chimeric (human-murine) immunoglobulin G1κ
(IgG1κ) monoclonal antibody:
Treatment of multicentric Castleman’s disease
(MCD) | | Drug interactions | Potentially hazardous interactions with other drugs
Live vaccines: risk of generalised infections - avoid.
Ciclosporin and tacrolimus: monitor levels on
initiation and discontinuation of siltuximab as it may
reduce the activity of CYP450. | | Metabolism | As siltuximab is a monoclonal antibody, the expected
consequence of metabolism is proteolytic degradation to
small peptides and individual amino acids, and receptormediated clearance. |
| | Siltuximab Preparation Products And Raw materials |
|