| Company Name: |
Focus Biomolecules
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855-362-8721 |
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sales@focusbiomolecules.com |
| Products Intro: |
Product Name:KL101
CAS:396721-89-4
Purity:>98% by HPLCNMR (Conforms) Package:$70.00/5mg;$305.00/25mg;
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| | Benzamide, N-[2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl- Basic information |
| Product Name: | Benzamide, N-[2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl- | | Synonyms: | Benzamide, N-[2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-;KL101 | | CAS: | 396721-89-4 | | MF: | C22H23N3OS | | MW: | 377.5 | | EINECS: | | | Product Categories: | | | Mol File: | 396721-89-4.mol | ![Benzamide, N-[2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl- Structure](CAS/20200611/GIF/396721-89-4.gif) |
| | Benzamide, N-[2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl- Chemical Properties |
| storage temp. | -20°C | | solubility | Soluble in DMSO (up to at least 25 mg/ml) | | form | solid | | color | White | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| | Benzamide, N-[2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl- Usage And Synthesis |
| Description | KL101 (396721-89-4) is an isoform-selective stabilizer of the circadian clock protein CRY1.? It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. KL101 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics. | | References | References/Citations: |
| | Benzamide, N-[2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl- Preparation Products And Raw materials |
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