Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:Z640 CAS:353793-07-4 Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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2-Quinoxalineacetamide, 1,2,3,4-tetrahydro-6,7-dimethyl-N-[4-(4-morpholinyl)phenyl]-3-oxo- manufacturers
- Z640
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- $1980.00 / 50mg
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2024-10-28
- CAS:353793-07-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| 2-Quinoxalineacetamide, 1,2,3,4-tetrahydro-6,7-dimethyl-N-[4-(4-morpholinyl)phenyl]-3-oxo- Basic information |
Product Name: | 2-Quinoxalineacetamide, 1,2,3,4-tetrahydro-6,7-dimethyl-N-[4-(4-morpholinyl)phenyl]-3-oxo- | Synonyms: | 2-Quinoxalineacetamide, 1,2,3,4-tetrahydro-6,7-dimethyl-N-[4-(4-morpholinyl)phenyl]-3-oxo-;Z640 | CAS: | 353793-07-4 | MF: | C22 H26 N4 O3 | MW: | 394.47 | EINECS: | | Product Categories: | | Mol File: | 353793-07-4.mol | |
| 2-Quinoxalineacetamide, 1,2,3,4-tetrahydro-6,7-dimethyl-N-[4-(4-morpholinyl)phenyl]-3-oxo- Chemical Properties |
Boiling point | 712.8±60.0 °C(Predicted) | density | 1.235±0.06 g/cm3(Predicted) | pka | 13.46±0.40(Predicted) |
| 2-Quinoxalineacetamide, 1,2,3,4-tetrahydro-6,7-dimethyl-N-[4-(4-morpholinyl)phenyl]-3-oxo- Usage And Synthesis |
Description | Z640 an aPKC agonist. Z640 was further confirmed as a non?selective aPKC agonist that can activate the kinase activity of both PKCι and PKCζ. In the cell?based assay, Z640 was found to protect neuronal cell lines from amyloid?β (Aβ) oligomer?induced cell death by reducing reactive oxygen species production and restore mitochondrial function. In addition, Z640 could reduce Aβ40 generation in a dose?dependent manner and shift amyloid precursor protein processing towards the non?amyloid pathway |
| 2-Quinoxalineacetamide, 1,2,3,4-tetrahydro-6,7-dimethyl-N-[4-(4-morpholinyl)phenyl]-3-oxo- Preparation Products And Raw materials |
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