Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:Aβ42-IN-2 CAS:1914989-80-2 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:Aβ42-IN-2;Aβ42 IN 2,Aβ42IN2 CAS:1914989-80-2 Purity:100% Package:100 mg;50 mg
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Company Name: |
RD International Technology Co., Limited
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Tel: |
18024082417 |
Email: |
market@ubiochem.com |
Products Intro: |
Product Name:Aβ42-IN-2 CAS:1914989-80-2 Purity:5mg;10mg;50mg;100mg;250mg;500mg;1g Package:5mg;10mg;50mg;100mg;250mg;500mg;1g
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| 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Basic information |
| 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Chemical Properties |
Boiling point | 651.4±55.0 °C(Predicted) | density | 1.23±0.1 g/cm3(Predicted) | storage temp. | 4°C, stored under nitrogen | solubility | DMSO : 20 mg/mL (46.46 mM; Need ultrasonic) | pka | 4.22±0.10(Predicted) |
| 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Usage And Synthesis |
Biological Activity | Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for αβ42. Aβ42-IN-2 can be used for the research of Alzheimer’s disease[1]. | References | [1]. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1. |
| 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Preparation Products And Raw materials |
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