ARV110 基本信息
中文名称 | ARV110 |
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中文同义词 | ARV110;N-[反式-4-(3-氯-4-氰基苯氧基)环己基]-6-[4-[[4-[2-(2,6-二氧-3-哌啶基)-6-氟] -2,3-二氢-1,3-二氧-1H-异吲哚-5-基]-1-哌嗪基]甲基]-1-哌啶基]-3-哒嗪甲酰胺;化合物ARV-110;N-(反式-4-(3-氯-4-氰基苯氧基)环己基)-6-(4-((4-(2-(2,6-二氧代哌啶-3-基)-6-氟-1,3-二氧代异吲哚啉-5-基)哌嗪-1-基)甲基)哌啶-1-基)哒嗪-3-甲酰胺 |
英文名称 | 3-Pyridazinecarboxamide, N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]- |
英文同义词 | 3-Pyridazinecarboxamide, N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]-;N-((1R,4R)-4-(3-chloro-4-cyanophenox y)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopip eridin-3-yl)-6-fluoro-1,3-dioxoisoindoli n-5-yl)piperazin-1-yl)methyl)piperidin-1 -yl)pyridazine-3-carboxamide;N-(trans-4-(3-Chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide;ARV-110;Bavdegalutamide;Bavdegalutamide (ARV-110);3-Pyridazinecarboxamide, N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]...;prostate,castration-resistant prostate cancer,receptor,ARV 110,androgen,Bavdegalutamide,Androgen Receptor,inhibit,cancer,ARV110,Inhibitor,metastatic |
CAS号 | 2222112-77-6 |
分子式 | C41H43ClFN9O6 |
分子量 | 812.29 |
EINECS号 | |
相关类别 | 药物肽;化学品;有机化学 |
Mol文件 | 2222112-77-6.mol |
结构式 | ![]() |
ARV110 性质
沸点 | 1074.1±65.0 °C(Predicted) |
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密度 | 1.49±0.1 g/cm3(Predicted) |
储存条件 | Store at-20°C, away from moisture |
溶解度 | DMSO:26.67 mg/mL(32.83 mM;超声波和加温,用 HCl 调节 pH 至 3,并加热至 80°C) |
酸度系数(pKa) | 10.59±0.40(Predicted) |
形态 | 固体 |
颜色 | 浅黄至黄色 |
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/04/30 | HY-138641 | ARV110 Bavdegalutamide | 2222112-77-6 | 5 mg | 1460元 |
2024/04/30 | HY-138641 | ARV110 Bavdegalutamide | 2222112-77-6 | 10 mg | 2270元 |