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Xi'an Confluore Biological Technology Co., Ltd.
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+86-156-80926068 +86-15680926068 |
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1924344760@qq.com |
| Products Intro: |
Product Name:Hydroxy-PEG16-t-butyl ester
CAS:2592433-80-0
Purity:95% HPLC Package:10MG;25MG;50MG;100MG;1G;5G
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Hydroxy-PEG16-t-butyl ester manufacturers
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| | Hydroxy-PEG16-t-butyl ester Basic information |
| Product Name: | Hydroxy-PEG16-t-butyl ester | | Synonyms: | Hydroxy-PEG16-t-butyl ester ISO 9001：2015 REACH;4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49-Hexadecaoxahenpentacontanoic acid, 51-hydroxy-, 1,1-dimethylethyl ester | | CAS: | 2592433-80-0 | | MF: | C39H78O19 | | MW: | 851.03 | | EINECS: | | | Product Categories: | | | Mol File: | 2592433-80-0.mol |  |
| | Hydroxy-PEG16-t-butyl ester Chemical Properties |
| Boiling point | 774.9±55.0 °C(Predicted) | | density | 1.097±0.06 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) |
| | Hydroxy-PEG16-t-butyl ester Usage And Synthesis |
| Uses | Hydroxy-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Hydroxy-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
| | Hydroxy-PEG16-t-butyl ester Preparation Products And Raw materials |
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