Log in | Join Free | china | japan | germany

3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester

Request For Quotation
3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester
CAS:303141-21-1
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:DC-S239
CAS:303141-21-1
Purity:99.36% Package:1mg;58USD|5mg;148USD|10mg;238USD
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:DC-S239
CAS:303141-21-1
Purity:99% Package:$300.9/5mg;$480.9/10mg;$950.9/25mg;$1450.9/50mg;Bulk package Remarks:99%
Company Name: Guangzhou Ruitai Chemical Co., Ltd.  Gold
Tel: 18344585702
Email: 550795326@qq.com
Products Intro: Product Name:3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester
CAS:303141-21-1
Purity:98% Package:1g/RMB 1200;5g/RMB 4500
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Email:
Products Intro: Product Name:DC-S239
CAS:303141-21-1
Purity:98% HPLC Package:5mg，10mg，50mg，100mg，1g，5g

3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester manufacturers

  • DC-S239
  • DC-S239 pictures
  • $97.00 / 1mg
  • 2024-11-19
  • CAS:303141-21-1
  • Min. Order:
  • Purity: 99.36%
  • Supply Ability: 10g
3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester Basic information
Product Name:3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester
Synonyms:3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester;DC-S239;Ethyl 2-amino-4-methyl-5-[(3-nitrophenyl)carbamoyl]thiophene-3-carboxylate;Histone Methyltransferase,Ethyl 2 amino 4 methyl 5 [(3 nitrophenyl)carbamoyl]thiophene 3 carboxylate,anti-cancer,HL60,SET7 inhibitor,MV4-11,MCF7,Ethyl 2amino4methyl5[(3nitrophenyl)carbamoyl]thiophene3carboxylate,inhibit,Inhibitor
CAS:303141-21-1
MF:C15H15N3O5S
MW:349.36
EINECS:
Product Categories:
Mol File:303141-21-1.mol
3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester Structure
3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester Chemical Properties
Boiling point 479.4±45.0 °C(Predicted)
density 1.440±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 125 mg/mL (357.80 mM; Need ultrasonic)
pka11.12±0.70(Predicted)
form Solid
color Yellow to orange
Safety Information
MSDS Information
3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester Usage And Synthesis
Biological ActivityDC-S239 is a selective histone methyltransferase SET7 inhibitor with an IC50 value of 4.59 μM. DC-S239 also displays selectivity for DNMT1, DOT1L, EZH2, NSD1, SETD8 and G9a. DC-S239 has anticancer activity[1]. DC-S239 inhibits DNMT1, DOT1L, EZH2, NSD1, SETD8 and G9a by less than 45%, while it inhibits SET7 by 90% at concentrations of 100 μM[1].DC-S239 (0-100 μM, 120 h) can inhibit the proliferation of MCF7, HL60 and MV4-11 cells in a dose-dependent manner but no significant effect on the activity of HCT116 and DHL4 cells[1].
References[1]. Fanwang Meng, et al. Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening. J Med Chem. 2015 Oct 22;58(20):8166-81.
3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester Preparation Products And Raw materials
Tag:3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-[[(3-nitrophenyl)amino]carbonyl]-, ethyl ester(303141-21-1) Related Product Information