Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester

Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Suppliers list
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Products Intro: Product Name:Preterramide C
CAS:81469-77-4
Purity:>95% by HPLC Remarks:0
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
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Products Intro: Product Name:Preterramide C
CAS:81469-77-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: Beijing Biocreative Technology Co., Ltd.  
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Products Intro: Product Name:Preterramide C
CAS:81469-77-4
Purity:99% HPLC Package:1.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 2.0g; 5.0g;
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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Products Intro: Product Name:Preterramide C
CAS:81469-77-4
Purity:95% Package:250μg;1mg
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Products Intro: Product Name:Preterramide C
CAS:81469-77-4
Purity:97% Package:1g
Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Basic information
Product Name:Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester
Synonyms:Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester;Preterramide C;3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-benzoic acid, methyl ester
CAS:81469-77-4
MF:C24H23N3O7
MW:465.46
EINECS:
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Mol File:81469-77-4.mol
Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Structure
Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Chemical Properties
Boiling point 532.2±50.0 °C(Predicted)
density 1.328±0.06 g/cm3(Predicted)
storage temp. -20°C
form A solid
pka10.73±0.70(Predicted)
Safety Information
MSDS Information
Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Usage And Synthesis
Biological ActivityPreterramide C is a fungal metabolite that has been found in A. terreus.1 It is active against S. aureus (MIC = 52.4 μM) but not E. aerogenes, P. aeruginosa, or C. albicans (MICs = >100 μM for all).2 Preterramide C inhibits the growth of L5178Y mouse lymphoma cells with an IC50 value of 0.1 μg/ml.3 It also inhibits nitric oxide (NO) production induced by LPS in RAW 264.7 cells (IC50 = 5.48 μM).
References1.He, F., Bao, J., Zhang, X.-Y., et al.Asperterrestide A, a cytotoxic cyclic tetrapeptide from the marine-derived fungus Aspergillus terreus SCSGAF0162J. Nat. Prod.76(6)1182-1186(2013) 2.Wang, Y., Zheng, J., Liu, P., et al.Three new compounds from Aspergillus terreus PT06-2 grown in a high salt mediumMar. Drugs9(8)1368-1378(2011) 3.Zhou, Y., Mandi, A., Debbab, A., et al.New austalides from the sponge-associated fungus Aspergillus sp.Eur. J. Org. Chem.306009-6019(2011)
Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Preparation Products And Raw materials
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