![CYTISINE](/ProductImageEN/2024-03/Large/42597045-161c-4f33-977a-70311bd55ba2.gif)
CYTISINE NEW
Price | $6 | $5 | $1 |
Package | 1KG | 25KG | 100KG |
Min. Order: | 1KG |
Supply Ability: | g-kg-tons, free sample is available |
Update Time: | 2024-03-29 |
Product Details
Product Name: CYTISINE | CAS No.: 485-35-8 |
Min. Order: 1KG | Purity: 99% |
Supply Ability: g-kg-tons, free sample is available | Release date: 2024/03/29 |
Lead time: In stock | Packaging: bottle/drum/bucket/IBC, as request. |
Delivery: By sea, by air, by express | Origin: Manufacturer |
Name: Sun |
1. Product information
Name | cytisine |
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Synonym | More Synonyms |
Description | Cytisine is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus. Cytisine is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. has been used medically to help with smoking cessation[3]. |
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Related Catalog | Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Metabolic Disease |
Target | α4β2 nAChRs[1]. |
In Vitro | Cytisine (2.5, 5 and 10 mM) is capable of inducing apoptosis in HepG2 cells[4]. Treatment with Cytisine increases the percentage of cells in the sub-G1 phase (P<0.01). The preincubation of HepG2 cells with Cytisine (2.5, 5 and 10 mM) significantly increases the sub-G1 cell population[4]. |
In Vivo | Cytisine (5 mg/kg, i.p.) eat less and gain less weight than those that receive the vehicle[2]. Total pellet intake increases during Cytisine substitution relative to nicotine and animals self-administered Cytisine significantly less than nicotine[2]. |
References | [1]. Pabreza LA, et al. [3H]cytisine binding to nicotinic cholinergic receptors in brain. Mol Pharmacol. 1991 Jan;39(1):9-12. [2]. Grebenstein PE, et al. The effects of noncontingent and self-administered cytisine on body weight and meal patterns in male Sprague-Dawley rats. Pharmacol Biochem Behav. 2013 Sep;110:192-200. [3]. Walker N, et al. Cytisine versus nicotine for smoking cessation. N Engl J Med. 2014 Dec 18;371(25):2353-62. [4]. Yu L, et al. Cytisine induces endoplasmic reticulum stress caused by calcium overload in HepG2 cells. Oncol Rep. 2018 Mar;39(3):1475-1484. |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 413.0±34.0 °C at 760 mmHg |
Melting Point | 154-156ºC |
Molecular Formula | C11H14N2O |
Molecular Weight | 190.242 |
Flash Point | 203.6±25.7 °C |
Exact Mass | 190.110611 |
PSA | 34.03000 |
LogP | 0.07 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.623 |
Cytisine MSDS(Chinese) |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol | ![]() GHS06 |
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Signal Word | Danger |
Hazard Statements | H301-H315-H319-H335 |
Precautionary Statements | P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
Hazard Codes | T:Toxic |
Risk Phrases | R25;R36/37/38 |
Safety Phrases | S26-S28-S36/37-S45 |
RIDADR | UN 2811 |
WGK Germany | 3 |
RTECS | HA4025000 |
Packaging Group | III |
Hazard Class | 6.1(b) |
HS Code | 2933990090 |
![]() (6R,7R,9R)-(-)-... 667940-15-0 ~79% ![]() Cytisine 485-35-8 |
Literature: Danieli, Bruno; Lesma, Giordano; Passarella, Daniele; Sacchetti, Alessandro; Silvani, Alessandra; Virdis, Andrea Organic Letters, 2004 , vol. 6, # 4 p. 493 - 496 |
![]() (3S,5R)-(+)-3-a... 206554-22-5 ~% ![]() Cytisine 485-35-8 |
Literature: Danieli, Bruno; Lesma, Giordano; Passarella, Daniele; Sacchetti, Alessandro; Silvani, Alessandra; Virdis, Andrea Organic Letters, 2004 , vol. 6, # 4 p. 493 - 496 |
![]() (3S,5R,1'S)... 667940-16-1 ~% ![]() Cytisine 485-35-8 |
Literature: Danieli, Bruno; Lesma, Giordano; Passarella, Daniele; Sacchetti, Alessandro; Silvani, Alessandra; Virdis, Andrea Organic Letters, 2004 , vol. 6, # 4 p. 493 - 496 |
Precursor 9 | Previous 1/3 Next |
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DownStream 3 | |
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HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Email address : Sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 86 13526505137
Company Profile Introduction
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- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro